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SERPINB6 Rabbit pAb

Anti-SERPINB6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217807

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217807
Product Name:   Anti-SERPINB6 Rabbit Polyclonal Antibody
Synonyms:   CAP; PI6; PTI; PI-6; SPI3; DFNB91; MSTP057
UNIPROT ID:   P35237 (Gene Accession – BC001394 )
Background:    The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.
Immunogen:    Fusion protein of human SERPINB6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217807(SERPINB6 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217807(Anti-SERPINB6 Antibody) at dilution 1/35.
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