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SESN3 Rabbit pAb

Anti-SESN3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217811

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217811
Product Name:   Anti-SESN3 Rabbit Polyclonal Antibody
Synonyms:   SEST3
UNIPROT ID:   P58005 (Gene Accession – BC017296 )
Background:    This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.
Immunogen:    Fusion protein of human SESN3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 100-300;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Metabolism, Cell Biology, Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217811(SESN3 Antibody) at a dilution of 1/110(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217811(Anti-SESN3 Antibody) at dilution 1/110.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 217811(Anti-SESN3 Antibody) at a dilution of 1/110.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D223138(Anti-SESN3 Antibody) at dilution 1/110.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Mouse heart tissue lysate;
Primary antibody: 217811(SESN3 Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 30 seconds
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