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SETD1A Rabbit pAb

Anti-SETD1A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222203

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222203
Product Name:   Anti-SETD1A Rabbit Polyclonal Antibody
Synonyms:   Set1; KMT2F; Set1A
UNIPROT ID:   O15047 (Gene Accession – NP_055527 )
Background:    The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.
Immunogen:    Synthetic peptide of human SETD1A
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 222203(SETD1A Antibody) at a dilution of 1/40(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 222203(Anti-SETD1A Antibody) at dilution 1/40.
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