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SH2B2 Rabbit pAb

Anti-SH2B2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220388

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220388
Product Name:   Anti-SH2B2 Rabbit Polyclonal Antibody
Synonyms:   APS
UNIPROT ID:   O14492 (Gene Accession – NP_066189 )
Background:    The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt’s lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.
Immunogen:    Synthetic peptide of human SH2B2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 15-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220388(SH2B2 Antibody) at a dilution of 1/15(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220388(Anti-SH2B2 Antibody) at dilution 1/15.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 220388(Anti-SH2B2 Antibody) at a dilution of 1/15.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with synthetic peptide and then with D261464(Anti-SH2B2 Antibody) at dilution 1/15.
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