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SLC47A1 Rabbit pAb

Anti-SLC47A1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216147

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216147
Product Name:   Anti-SLC47A1 Rabbit Polyclonal Antibody
Synonyms:   MATE1
UNIPROT ID:   Q96FL8 (Gene Accession – NP_060712 )
Background:    Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4′-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes. This gene is located within the Smith-Magenis syndrome region on chromosome 17.
Immunogen:    Synthetic peptide of human SLC47A1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-50;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 216147(SLC47A1 Antibody) at a dilution of 1/50(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the synthetic peptide and then with 216147(Anti-SLC47A1 Antibody) at dilution 1/50.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-4: 293T, Hela, HepG2, A549 cell lysates;
Primary antibody: 216147(SLC47A1 Antibody) at dilution 1/400;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds
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