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SMAC Rabbit mAb

Anti-SMAC Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262909

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262909
Product Name:   Anti-SMAC Rabbit Monoclonal Antibody
Synonyms:   SMAC; DFNA64; DIABLO; SMAC3
UNIPROT ID:   Q9NR28
Background:    Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases.
Immunogen:    A synthetic peptide of human Smac/Diablo
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R08-6A3
MW:    Calculated MW: 27 kDa; Observed MW: 21 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    apoptosis – Caspase family
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Smac/Diablo(green) in Hela using Smac/Diablo antibody,and DAPI(blue)

Western blot analysis of Smac/Diablo in mouse heart, rat skin lysates using SMAC antibody.

Western blot analysis of Smac/Diablo in K562, Hela lysates using Smac/Diablo antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using Smac/Diablo antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
          Publications