Email: info@neweastbio.com   |  Call: 6109452007

SMC1A (4C5) Mouse mAb

Anti-SMC1A (4C5) Mouse Monoclonal Antibody
5/5

$349.00

Cat.#:  N261019

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261019
Product Name:   Anti-SMC1A (4C5) Mouse Monoclonal Antibody
Synonyms:   Chromosome segregation protein SmcB; DXS423E; KIAA0178; MGC138332; Sb1.8; Segregation of mitotic chromosomes 1; SMC protein 1A; SMC-1-alpha; SMC-1A; SMC1 (structural maintenance of chromosomes 1 yeast) like 1; SMC1; SMC1 structural maintenance of chromosomes 1 like 1; SMC1A; SMC1A_HUMAN; SMC1alpha; SMC1L1; SMCB; Structural maintenance of chromosomes 1A; Structural maintenance of chromosomes protein 1A.
UNIPROT ID:   Q14683
Background:    Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair . ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint. SMC1 phosphorylation is ATM-independent in cells subjected to other forms of DNA damage, including UV light and hydroxyurea treatment.
Immunogen:    Purified recombinant human SMC1A(C-term.) protein fragments expressed in E.coli.
Applications:    WB,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200
Host Species:    Mouse
Clonality:    Mouse Monoclonal
Clone ID:    4C5-C8-A11
MW:    Calculated MW: 143 kDa; Observed MW: 143 kDa
Isotype:    IgG1
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of SMC1A (4C5) in HeLa using SMC1A antibody.

Western blot analysis of SMC1A(Cterm) in MOLT4, U87 MG and HelaNE lysates using SMC1A (Nterminus) antibody.
          Publications