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SNAI1 Rabbit pAb

Anti-SNAI1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225404

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225404
Product Name:   Anti-SNAI1 Rabbit pAb
Synonyms:   SNAH; Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna
UNIPROT ID:   O95863
Background:    Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells . Indeed, loss of E-cadherin expression is correlated with the invasive properties of some tumors and there is a considerable inverse correlation between Snail and E-cadherin mRNA levels in epithelial tumor cell lines . In addition, Snail blocks the cell cycle and confers resistance to cell death . Phosphorylation of Snail by GSK-3 and PAK1 regulates its stability, cellular localization and function .Tissue specificity: Expressed in a variety of tissues with the highest expression in kidney.
Immunogen:    The antiserum was produced against synthesized peptide derived from human SNAI1. AA range:215-264
Applications:    WB,IHC-P,ICC/IF,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 29 kDa; Observed MW: 29 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of SNAI1 in 3T3 lysates using SNAI1 antibody.
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