NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N261116 | ||
Product Name: Anti-STAT1 (6C2) Mouse Monoclonal Antibody | ||
Synonyms: STAT1; Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84 | ||
UNIPROT ID: P42224 | ||
Background: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. | ||
Immunogen: Purified recombinant human STAT1 protein fragments expressed in E.coli | ||
Applications: WB,IP | ||
Recommended Dilutions: WB: 1/500-1/1000 IP: 1/20 | ||
Host Species: Mouse | ||
Clonality: Mouse Monoclonal | ||
Clone ID: 6C2-F7-D12 | ||
MW: Calculated MW: 87 kDa; Observed MW: 91 kDa | ||
Isotype: IgG2a | ||
Purification: Affinity Purified | ||
Species Reactivity: Human,Monkey | ||
Conjugation: Unconjugated | ||
Modification: Unmodified | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
Research Areas: Signal Transduction | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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