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STEAP2 Rabbit pAb

Anti-STEAP2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S215151

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S215151
Product Name:   Anti-STEAP2 Rabbit Polyclonal Antibody
Synonyms:   STMP; IPCA1; PUMPCn; STAMP1; PCANAP1
UNIPROT ID:   Q8NFT2 (Gene Accession – NP_001035755 )
Background:    This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi comple,x the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Immunogen:    Synthetic peptide of human STEAP2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-100;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 215151(STEAP2 Antibody) at a dilution of 1/35(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 215151(Anti-STEAP2 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 215151(Anti-STEAP2 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D162955(Anti-STEAP2 Antibody) at dilution 1/35.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Human stomach tissue, Human placenta tissue lysates;
Primary antibody: 215151(STEAP2 Antibody) at dilution 1/400;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 minutes
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