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STXBP2 Rabbit pAb

Anti-STXBP2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216879

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216879
Product Name:   Anti-STXBP2 Rabbit Polyclonal Antibody
Synonyms:   FHL5; UNC18B; Hunc18b; UNC18-2; pp10122; MUNC18-2
UNIPROT ID:   Q15833 (Gene Accession – BC002869 )
Background:    This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Immunogen:    Fusion protein of human STXBP2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216879(STXBP2 Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216879(Anti-STXBP2 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 216879(Anti-STXBP2 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D221402(Anti-STXBP2 Antibody) at dilution 1/20.

Gel: 10%SDS-PAGE, Lysate: 50 μg;
Lane 1-3: A549 cells, human liver cancer tissue, Hela cells;
Primary antibody: 216879(STXBP2 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 40 seconds
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