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STXBP4 Rabbit pAb

Anti-STXBP4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217873

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217873
Product Name:   Anti-STXBP4 Rabbit Polyclonal Antibody
Synonyms:   Synip
UNIPROT ID:   Q6ZWJ1 (Gene Accession – BC125116 )
Background:    Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
Immunogen:    Fusion protein of human STXBP4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217873(STXBP4 Antibody) at a dilution of 1/40(Cell membrane and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217873(Anti-STXBP4 Antibody) at dilution 1/40.
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