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SUCLA2 Rabbit pAb

Anti-SUCLA2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219475

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219475
Product Name:   Anti-SUCLA2 Rabbit Polyclonal Antibody
Synonyms:   A-SCS; A-BETA; MTDPS5; LINC00444; SCS-betaA
UNIPROT ID:   Q9P2R7 (Gene Accession – BC027587 )
Background:    Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.
Immunogen:    Fusion protein of human SUCLA2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-100;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Neuroscience, Cardiovascular, Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 219475(SUCLA2 Antibody) at a dilution of 1/65(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the fusion protein and then with 219475(Anti-SUCLA2 Antibody) at dilution 1/65.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 219475(Anti-SUCLA2 Antibody) at a dilution of 1/65.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with fusion protein and then with D227293(Anti-SUCLA2 Antibody) at dilution 1/65.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Human placenta tissue lysate;
Primary antibody: 219475(SUCLA2 Antibody) at dilution 1/600;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 2 minutes
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