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SYCP3 Rabbit pAb

Anti-SYCP3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220884

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220884
Product Name:   Anti-SYCP3 Rabbit Polyclonal Antibody
Synonyms:   COR1; SCP3; SPGF4; RPRGL4
UNIPROT ID:   Q8IZU3 (Gene Accession – NP_001171419 )
Background:    This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
Immunogen:    Synthetic peptide of human SYCP3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-100;WB: 500-2000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling,Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 220884(SYCP3 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the synthetic peptide and then with 220884(Anti-SYCP3 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 220884(Anti-SYCP3 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with synthetic peptide and then with D262171(Anti-SYCP3 Antibody) at dilution 1/50.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-6: K562 cell, Human seminoma tissue, Jurkat cell, Mouse testis tissue, HepG2 cell, TM4 cell lysates;
Primary antibody: 220884(SYCP3 Antibody) at dilution 1/550;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 20 seconds
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