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TADA3 Rabbit pAb

Anti-TADA3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218665

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218665
Product Name:   Anti-TADA3 Rabbit Polyclonal Antibody
Synonyms:   ADA3; NGG1; hADA3; STAF54; TADA3L
UNIPROT ID:   O75528 (Gene Accession – BC009240 )
Background:    DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the comple,x this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene.
Immunogen:    Fusion protein of human TADA3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 218665(TADA3 Antibody) at a dilution of 1/20(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 218665(Anti-TADA3 Antibody) at dilution 1/20.
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