NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S221002 | ||||
Product Name: Anti-TBC1D21 Rabbit Polyclonal Antibody | ||||
Synonyms: MgcRabGAP | ||||
UNIPROT ID: Q8IYX1 (Gene Accession – NP_699187 ) | ||||
Background: TBC1D21 gene (TBC1 domain family member 21) is located on human chromosome 15, acts as a GTPase-activating protein for Rab family proteins. Rab family proteins comprise G proteins of the Ras superfamily that belong to a protein superfamily of small GTPases. Approximately 70 types of Rabs have been identified in humans. They are regulators of membrane traffic, including vesicle formation, vesicle movement along actin and tubulin networks, and membrane fusion. | ||||
Immunogen: Synthetic peptide of human TBC1D21 | ||||
Applications: ELISA, IHC | ||||
Recommended Dilutions: IHC: 25-100; ELISA: 2000-5000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Signal Transduction | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
|