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TERF2 Rabbit pAb

Anti-TERF2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220011

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220011
Product Name:   Anti-TERF2 Rabbit Polyclonal Antibody
Synonyms:   TRF2; TRBF2
UNIPROT ID:   Q15554 (Gene Accession – NP_005643.2 )
Background:    This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
Immunogen:    Synthetic peptide of human TERF2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 220011(TERF2 Antibody) at a dilution of 1/50(Cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 220011(Anti-TERF2 Antibody) at dilution 1/50.
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