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TET2 Rabbit pAb

Anti-TET2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222422

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222422
Product Name:   Anti-TET2 Rabbit Polyclonal Antibody
Synonyms:   MDS; IMD75; KIAA1546
UNIPROT ID:   Q6N021 (Gene Accession – NP_001120680 )
Background:    The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene.
Immunogen:    Synthetic peptide of human TET2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 222422(TET2 Antibody) at a dilution of 1/50(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 222422(Anti-TET2 Antibody) at dilution 1/50.
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