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TFB2M Rabbit pAb

Anti-TFB2M Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219379

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219379
Product Name:   Anti-TFB2M Rabbit Polyclonal Antibody
Synonyms:   Hkp1; mtTFB2
UNIPROT ID:   Q9H5Q4 (Gene Accession – BC003383 )
Background:    S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
Immunogen:    Fusion protein of human TFB2M
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 219379(TFB2M Antibody) at a dilution of 1/85(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 219379(Anti-TFB2M Antibody) at dilution 1/85.
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