Email: info@neweastbio.com   |  Call: 6109452007

TIA1 Rabbit pAb

Anti-TIA1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217901

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217901
Product Name:   Anti-TIA1 Rabbit Polyclonal Antibody
Synonyms:   WDM; ALS26; TIA-1
UNIPROT ID:   P31483 (Gene Accession – BC015944 )
Background:    The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene.
Immunogen:    Fusion protein of human TIA1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 217901(TIA1 Antibody) at a dilution of 1/65(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the fusion protein and then with 217901(Anti-TIA1 Antibody) at dilution 1/65.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 217901(Anti-TIA1 Antibody) at a dilution of 1/65.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D223330(Anti-TIA1 Antibody) at dilution 1/65.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: LOVO, Hela, PC-3 cell lysates;
Primary antibody: 217901(TIA1 Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 20 seconds
          Publications