Email: info@neweastbio.com   |  Call: 6109452007

TMEM123 Rabbit pAb

Anti-TMEM123 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S211436

   Size:   100 μl

In Stock

Out of stock

          Product Description          
Cat.#:   S211436
Product Name:   Anti-TMEM123 Rabbit Polyclonal Antibody
Synonyms:   KCT3; PORMIN; PORIMIN
UNIPROT ID:   Q8N131 (Gene Accession – BC032296 )
Background:    This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
Immunogen:    Fusion protein of human TMEM123
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 211436(TMEM123 Antibody) at a dilution of 1/25(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 211436(Anti-TMEM123 Antibody) at dilution 1/25.
          Publications