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TMPRSS11B Rabbit pAb

Anti-TMPRSS11B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217926

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217926
Product Name:   Anti-TMPRSS11B Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   Q86T26 (Gene Accession – BC126195 )
Background:    TMPRSS11B (transmembrane protease serine 11B), also known as airway trypsin-like protease 5, is a 416 amino acid single-pass type II membrane protein that belongs to the peptidase S1 family and contains one peptidase S1 domain and one SEA domain. The gene that encodes TMPRSS11B consists of over 19,000 bases and maps to human chromosome 4q13.2. Chromosome 4 represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington’s disease, is encoded by a gene that maps to chromosome 4. FGFR-3 is also encoded by a gene located on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Immunogen:    Fusion protein of human TMPRSS11B
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217926(TMPRSS11B Antibody) at a dilution of 1/20(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217926(Anti-TMPRSS11B Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 217926(Anti-TMPRSS11B Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with fusion protein and then with D223381(Anti-TMPRSS11B Antibody) at dilution 1/20.
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