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TNFAIP3 Rabbit pAb

Anti-TNFAIP3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216143

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216143
Product Name:   Anti-TNFAIP3 Rabbit Polyclonal Antibody
Synonyms:   A20; AISBL; OTUD7C; TNFA1P2
UNIPROT ID:   P21580 (Gene Accession – NP_006281 )
Background:    This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene.
Immunogen:    Synthetic peptide of human TNFAIP3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 216143(TNFAIP3 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 216143(Anti-TNFAIP3 Antibody) at dilution 1/50.
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