Email: info@neweastbio.com   |  Call: 6109452007

TNFRSF13C Rabbit pAb

Anti-TNFRSF13C Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220749

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220749
Product Name:   Anti-TNFRSF13C Rabbit Polyclonal Antibody
Synonyms:   BAFFR; CD268; CVID4; BAFF-R; BROMIX; prolixin
UNIPROT ID:   Q96RJ3 (Gene Accession – NP_443177 )
Background:    B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Immunogen:    Synthetic peptide of human TNFRSF13C
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 220749(TNFRSF13C Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 220749(Anti-TNFRSF13C Antibody) at dilution 1/40.
          Publications