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TNFRSF8 Rabbit pAb

Anti-TNFRSF8 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220434

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220434
Product Name:   Anti-TNFRSF8 Rabbit Polyclonal Antibody
Synonyms:   CD30; Ki-1; D1S166E
UNIPROT ID:   P28908 (Gene Accession – NP_001234 )
Background:    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Immunogen:    Synthetic peptide of human TNFRSF8
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer, Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human Lymphoma tissue using 220434(TNFRSF8 Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human Lymphoma tissue is first treated with the synthetic peptide and then with 220434(Anti-TNFRSF8 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 220434(Anti-TNFRSF8 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D261524(Anti-TNFRSF8 Antibody) at dilution 1/50.
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