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TP53BP2 Rabbit pAb

Anti-TP53BP2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217191

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217191
Product Name:   Anti-TP53BP2 Rabbit Polyclonal Antibody
Synonyms:   BBP; 53BP2; ASPP2; P53BP2; PPP1R13A
UNIPROT ID:   Q13625 (Gene Accession – BC040247 )
Background:    This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human TP53BP2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217191(TP53BP2 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217191(Anti-TP53BP2 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 217191(Anti-TP53BP2 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with fusion protein and then with D221955(Anti-TP53BP2 Antibody) at dilution 1/35.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: Mouse kidney tissue, 293T cells, 231 cells;
Primary antibody: 217191(TP53BP2 Antibody) at dilution 1/375;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 30 seconds
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