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TPM2 Rabbit pAb

Anti-TPM2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S219790

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S219790
Product Name:   Anti-TPM2 Rabbit Polyclonal Antibody
Synonyms:   DA1, DA2B, NEM4, TMSB, AMCD1
UNIPROT ID:   P07951 (Gene Accession – NP_998839 )
Background:    This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. TPM2 has been shown to interact with RRAD, PDLIM7 and TPM1.
Immunogen:    Synthetic peptide of human TPM2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 1000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219790(TPM2 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 219790(Anti-TPM2 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 219790(Anti-TPM2 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D260374(Anti-TPM2 Antibody) at dilution 1/35.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane: Human cervical cancer tissue;
Primary antibody: 219790(TPM2 Antibody) at dilution 1/750;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 2 minutes
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