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TPM4 Rabbit pAb

Anti-TPM4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218212

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218212
Product Name:   Anti-TPM4 Rabbit Polyclonal Antibody
Synonyms:   HEL-S-108
UNIPROT ID:   P67936 (Gene Accession – BC037576 )
Background:    This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
Immunogen:    Fusion protein of human TPM4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 218212(TPM4 Antibody) at a dilution of 1/110(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 218212(Anti-TPM4 Antibody) at dilution 1/110.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 218212(Anti-TPM4 Antibody) at a dilution of 1/110.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D223959(Anti-TPM4 Antibody) at dilution 1/110.
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