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TPR Rabbit pAb

Anti-TPR Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220766

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220766
Product Name:   Anti-TPR Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   P12270 (Gene Accession – NP_003283 )
Background:    This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5′ end of this gene with several different kinase genes occur in some neoplasias.
Immunogen:    Synthetic peptide of human TPR
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 220766(TPR Antibody) at a dilution of 1/20(Nucleus and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 220766(Anti-TPR Antibody) at dilution 1/20.
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