Email: info@neweastbio.com   |  Call: 6109452007

Transcription Factor 7 Like 2 Rabbit pAb

Anti-Transcription Factor 7 Like 2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225697

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225697
Product Name:   Anti-Transcription Factor 7 Like 2 Rabbit pAb
Synonyms:   TCF7L2; HMG box transcription factor 4; HTCF-4; T-cell factor-4 variant X2; T-cell factor 4; Transcription factor 7-like 2; TCF-4
UNIPROT ID:   Q9NQB0
Background:    Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5′-CCTTTGATC-3′ in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1.
Immunogen:    A synthesized peptide derived from human TCF7L2
Applications:    WB,IHC-P,ICC/IF,IP,FC
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 68 kDa; Observed MW: 68 kDa
Isotype:    IgG
Purification:    Affinity Chromatography
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human colonic cancer using TCF7L2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of TCF7L2 in Jurkat lysates using Transcription Factor 7 Like 2 antibody.
          Publications