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TRIF Rabbit mAb

Anti-TRIF Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263021

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263021
Product Name:   Anti-TRIF Rabbit Monoclonal Antibody
Synonyms:   TRIF; IIAE6; MyD88-3; PRVTIRB; TICAM-1
UNIPROT ID:   Q8IUC6
Background:    Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines .
Immunogen:    Recombinant protein of human TRIF
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R02-2A9
MW:    Calculated MW: 76 kDa; Observed MW: 98 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of TRIF in K562, 3T3, Hela lysates using TRIF antibody.

Western blot analysis of TRIF in rat testis lysates using TRIF antibody.
          Publications