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TRIM22 Rabbit pAb

Anti-TRIM22 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221018

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221018
Product Name:   Anti-TRIM22 Rabbit Polyclonal Antibody
Synonyms:   RNF94; STAF50; GPSTAF50
UNIPROT ID:   Q8IYM9 (Gene Accession – NP_006065 )
Background:    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon’s antiviral effects.
Immunogen:    Synthetic peptide of human TRIM22
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology, Stem Cells
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 221018(TRIM22 Antibody) at a dilution of 1/25(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 221018(Anti-TRIM22 Antibody) at dilution 1/25.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: A172 cells;
Primary antibody: 221018(TRIM22 Antibody) at dilution 1/250;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 3 minutes
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