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TRIM25 Rabbit mAb

Anti-TRIM25 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263025

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263025
Product Name:   Anti-TRIM25 Rabbit Monoclonal Antibody
Synonyms:   TRIM25; EFP; RNF147; ZNF147; E3 ubiquitin/ISG15 ligase TRIM25; Estrogen-responsive finger protein; RING finger protein 147; Tripartite motif-containing protein 25; Ubiquitin/ISG15-conjugating enzyme TRIM25; Zinc finger protein 147
UNIPROT ID:   Q14258
Background:    Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates ‘Lys-63’-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.
Immunogen:    A synthetic peptide of human TRIM25
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R06-1H2
MW:    Calculated MW: 71 kDa; Observed MW: 71 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of TRIM25/EFP (green) in MCF-7 using TRIM25/EFP antibody,and DAPI(blue)

Western blot analysis of TRIM25/EFP in K562, rat Brain, C6, Hela lysates using TRIM25 antibody.
          Publications