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TRIM25 Rabbit pAb

Anti-TRIM25 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221021

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221021
Product Name:   Anti-TRIM25 Rabbit Polyclonal Antibody
Synonyms:   EFP; Z147; RNF147; ZNF147
UNIPROT ID:   Q14258 (Gene Accession – NP_005073 )
Background:    The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Immunogen:    Synthetic peptide of human TRIM25
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: Oct-50; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221021(TRIM25 Antibody) at a dilution of 1/25(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221021(Anti-TRIM25 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 221021(Anti-TRIM25 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with synthetic peptide and then with D262367(Anti-TRIM25 Antibody) at dilution 1/25.
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