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TRIM3 Rabbit pAb

Anti-TRIM3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220861

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220861
Product Name:   Anti-TRIM3 Rabbit Polyclonal Antibody
Synonyms:   BERP; HAC1; RNF22; RNF97
UNIPROT ID:   O75382 (Gene Accession – NP_001234935 )
Background:    The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also called the ‘RING-B-box-coiled-coil’ (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to cytoplasmic filaments. It is similar to a rat protein which is a specific partner for the tail domain of myosin V, a class of myosins which are involved in the targeted transport of organelles. The rat protein can also interact with alpha-actinin-4.
Immunogen:    Synthetic peptide of human TRIM3
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220861(TRIM3 Antibody) at a dilution of 1/40(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220861(Anti-TRIM3 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 220861(Anti-TRIM3 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with synthetic peptide and then with D262137(Anti-TRIM3 Antibody) at dilution 1/40.
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