NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S221024 | ||||||
Product Name: Anti-TRIM62 Rabbit Polyclonal Antibody | ||||||
Synonyms: DEAR1 | ||||||
UNIPROT ID: Q9BVG3 (Gene Accession – NP_060677 ) | ||||||
Background: TRIM62 (tripartite motif-containing 62) is a 475 amino acid protein that belongs to the TRIM/RBCC (Ring finger, B bo,x coiled-coil) family. TRIM62 contains one B box-type zinc finger, one SPRY domain and one RING-type zinc finger; a motif that has zinc-chelating activity and is involved in mediating protein-protein and protein-DNA interactions. As a member of the TRIM/RBCC family, TRIM62 may function in transcriptional regulation, cell transformation and carcinogenesis. In addition, TRIM62 expression can affect the entry of murine leukemia virus (MLV) and human immunodeficiency virus 1 (HIV). | ||||||
Immunogen: Synthetic peptide of human TRIM62 | ||||||
Applications: ELISA, WB, IHC | ||||||
Recommended Dilutions: IHC: 25-100;WB: 500-2000;ELISA: 2000-5000 | ||||||
Host Species: Rabbit | ||||||
Clonality: Rabbit Polyclonal | ||||||
Isotype: Immunogen-specific rabbit IgG | ||||||
Purification: Antigen affinity purification | ||||||
Species Reactivity: Human | ||||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||||
Research Areas: Cell Biology | ||||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||||
|