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TRPC5 Rabbit pAb

Anti-TRPC5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221055

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221055
Product Name:   Anti-TRPC5 Rabbit Polyclonal Antibody
Synonyms:   TRP5; PPP1R159
UNIPROT ID:   Q9UL62 (Gene Accession – NP_036603 )
Background:    This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1).
Immunogen:    Synthetic peptide of human TRPC5
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Signal Transduction, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 221055(TRPC5 Antibody) at a dilution of 1/35(Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 221055(Anti-TRPC5 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 221055(Anti-TRPC5 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with synthetic peptide and then with D262417(Anti-TRPC5 Antibody) at dilution 1/35.
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