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TRPC6 Rabbit pAb

Anti-TRPC6 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220241

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220241
Product Name:   Anti-TRPC6 Rabbit Polyclonal Antibody
Synonyms:   TRP6; FSGS2
UNIPROT ID:   Q9Y210 (Gene Accession – NP_004612 )
Background:    The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).
Immunogen:    Synthetic peptide of human TRPC6
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 3000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220241(TRPC6 Antibody) at a dilution of 1/50(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220241(Anti-TRPC6 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220241(Anti-TRPC6 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D261186(Anti-TRPC6 Antibody) at dilution 1/50.
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