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TSG101 Rabbit pAb

Anti-TSG101 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216868

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216868
Product Name:   Anti-TSG101 Rabbit Polyclonal Antibody
Synonyms:   TSG10; VPS23
UNIPROT ID:   Q99816 (Gene Accession – BC002487 )
Background:    The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.
Immunogen:    Fusion protein of human TSG101
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using 216868(TSG101 Antibody) at a dilution of 1/25(Cytoplasm or Nucleus).

Immunohistochemistry analysis of paraffin-embedded Human esophagus cancer tissue using 216868(Anti-TSG101 Antibody) at a dilution of 1/25.
          Publications