Email: info@neweastbio.com   |  Call: 6109452007

TXNDC5 Rabbit pAb

Anti-TXNDC5 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217963

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217963
Product Name:   Anti-TXNDC5 Rabbit Polyclonal Antibody
Synonyms:   HCC2; ERP46; HCC-2; STRF8; PDIA15; UNQ364; ENDOPDI
UNIPROT ID:   Q8NBS9 (Gene Accession – BC052310 )
Background:    This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
Immunogen:    Fusion protein of human TXNDC5
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 200-400;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 217963(TXNDC5 Antibody) at a dilution of 1/180(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 217963(Anti-TXNDC5 Antibody) at dilution 1/180.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-4: HT29, 293T, Hela cell, Human placenta tissue lysates;
Primary antibody: 217963(TXNDC5 Antibody) at dilution 1/1350;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds
          Publications