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UBE2Q2 Rabbit pAb

Anti-UBE2Q2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218307

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218307
Product Name:   Anti-UBE2Q2 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   Q8WVN8 (Gene Accession – BC017708 )
Background:    UBE2Q2 (Ubiquitin-conjugating enzyme E2 Q2) is a 375 amino acid cytoplasmic protein that is involved in ubiquitin-mediated protein degradation. Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). One of several members of the ubiquitin-conjugating enzyme family, UBE2Q2 is an E2 ubiquitin-conjugating enzyme that acts to catalyze the covalent attachment of ubiquitin residues to various proteins. UBE2Q2 expression is detected in invasive epithelial tissue and tumor masses including head and neck squamous cell carcinomas, suggesting a role for UBE2Q2 in carcinogenesis. Two isoforms of UBE2Q2 exist due to alternative splicing events.
Immunogen:    Fusion protein of human UBE2Q2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 218307(UBE2Q2 Antibody) at a dilution of 1/35(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the fusion protein and then with 218307(Anti-UBE2Q2 Antibody) at dilution 1/35.
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