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Ubiquitin Conjugating Enzyme E2 A/B Rabbit pAb

Anti-Ubiquitin Conjugating Enzyme E2 A/B Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225025

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225025
Product Name:   Anti-Ubiquitin Conjugating Enzyme E2 A/B Rabbit pAb
Synonyms:   UBE2A; RAD6A; Ubiquitin-conjugating enzyme E2 A; RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A; UBE2B; RAD6B; Ubiquitin-conjugating enzyme E2 B; RAD6 homolog B; HR6B; hHR6B; Ubiquitin carrier protein B; Ubiquitin-conjugating enzyme E2-17 kDa; Ubiquitin-protein ligase B
UNIPROT ID:   P49459/P63146
Background:    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at ‘Lys-120’ to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation.
Immunogen:    Synthesized peptide derived from the C-terminal region of human UBE2A/B.
Applications:    WB,IHC-P,ELISA
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 17 kDa; Observed MW: 17 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded rat brain using Ubiquitin Conjugating Enzyme E2 A/B antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Ubiquitin Conjugating Enzyme E2 A/B in Jurkat lysates using UBE2A/B antibody.

Immunohistochemistry analysis of paraffin-embedded rat brain using Ubiquitin Conjugating Enzyme E2 A/B antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded mouse brain using Ubiquitin Conjugating Enzyme E2 A/B antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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