NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S217973 | ||
Product Name: Anti-UBL4B Rabbit Polyclonal Antibody | ||
Synonyms: | ||
UNIPROT ID: Q8N7F7 (Gene Accession – BC058929 ) | ||
Background: Ubiquitin is a 77 amino acid protein that targets proteins for degradation by the 26S proteasome. Ubiquitin-like proteins are not directly involved in protein degradation, but appear to have many mechanistic similarities with the ubiquitin pathway. UBL4B (Ubiquitin-like protein 4B) is a 174 amino acid cytoplasmic protein that contains a ubiquitin-like domain. UBL4B likely arose by retroposition during mammalian evolution from UBL4A, an X-linked intron-bearing housekeeping gene. While UBL4A is highly conserved, UBL4B has undergone rapid evolution and may have evolved new functions. Expression of UBL4B is restricted to post-meiotic germ cells in testis and ovarian tissue, where it likely functions in post-translational protein modification. | ||
Immunogen: Full length fusion protein | ||
Applications: ELISA, IHC | ||
Recommended Dilutions: IHC: Oct-50; ELISA: 1000-2000 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Polyclonal | ||
Isotype: Immunogen-specific rabbit IgG | ||
Purification: Antigen affinity purification | ||
Species Reactivity: Human | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||
Research Areas: Cell Biology | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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