Email: info@neweastbio.com   |  Call: 6109452007

UBQLN1 Rabbit pAb

Anti-UBQLN1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217085

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217085
Product Name:   Anti-UBQLN1 Rabbit Polyclonal Antibody
Synonyms:   DA41; DSK2; UBQN; XDRP1; PLIC-1
UNIPROT ID:   Q9UMX0 (Gene Accession – BC039294 )
Background:    This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer’s and Parkinson’s disease. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human UBQLN1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-100;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217085(UBQLN1 Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217085(Anti-UBQLN1 Antibody) at dilution 1/60.

The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 217085(Anti-UBQLN1 Antibody) at a dilution of 1/60.

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with fusion protein and then with D221764(Anti-UBQLN1 Antibody) at dilution 1/60.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: A431 cell lysate;
Primary antibody: 217085(UBQLN1 Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 2 minutes
          Publications