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UBTD2 Rabbit pAb

Anti-UBTD2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221075

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221075
Product Name:   Anti-UBTD2 Rabbit Polyclonal Antibody
Synonyms:   DCUBP
UNIPROT ID:   Q8WUN7 (Gene Accession – NP_689490 )
Background:    UBTD2 (ubiquitin domain containing 2), also known as DCUBP (dendritic cell-derived ubiquitin-like protein), DC-UbP or SB72, is a 234 amino acid cytoplasmic and mitochondrial ubiquitin-like (UbL) protein that contains one C-terminal UbL domain. UbL proteins are involved in a variety of cellular processes, including DNA repair, protein sorting, apoptosis, protein degradation, cell division and autophagy. Predominantly expressed in dendritic cells and detected at high levels in tumor cell lines, UBTD2 has been implicated in apoptosis, cellular differentiation and tumorigenesis. The UbL domain of UBTD2 is 55% similar and 28.6% identical to the amino acid sequence of ubiquitin, but it lacks the Gly-Gly motif that is essential for ubiquitination. As its UbL domain does not actively ubiquitinate proteins, UBTD2 is believed to function as a shuttle factor involved in the ubiquitin system.
Immunogen:    Synthetic peptide of human UBTD2
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 30-150; ELISA: 2000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221075(UBTD2 Antibody) at a dilution of 1/40(Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221075(Anti-UBTD2 Antibody) at dilution 1/40.
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