Email: info@neweastbio.com   |  Call: 6109452007

USP45 Rabbit pAb

Anti-USP45 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217995

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217995
Product Name:   Anti-USP45 Rabbit Polyclonal Antibody
Synonyms:   
UNIPROT ID:   Q70EL2 (Gene Accession – BC005991 )
Background:    The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. A wide range of enzymes facilitate the proteolytic Ub pathway, including USPs (ubiquitin specific peptidases), which are cysteine proteases that are responsible for the release of ubiquitin from a ubiquitylated substrate and precursor fusion proteins. USP45 (Ubiquitin carboxyl-terminal hydrolase 45), also known as Deubiquitinating enzyme 45, is a 819 amino acid protein that is involved in ubiquitin-dependent protein catabolism. USP45 differs from other USPs in that it contains a UBP-type zinc finger, a domain which binds ubiquitin. Although USP45 is broadly expressed, the highest levels can be found in skeletal muscle, spleen and ovary. There are three isoforms of USP45 which are produced as a result of alternative splicing.
Immunogen:    Full length fusion protein
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human prostate cancer tissue using 217995(USP45 Antibody) at a dilution of 1/25(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with the fusion protein and then with 217995(Anti-USP45 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 217995(Anti-USP45 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with fusion protein and then with D223516(Anti-USP45 Antibody) at dilution 1/25.
          Publications