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VAMP2 Rabbit pAb

Anti-VAMP2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221100

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221100
Product Name:   Anti-VAMP2 Rabbit Polyclonal Antibody
Synonyms:   SYB2; VAMP-2; NEDHAHM
UNIPROT ID:   P63027 (Gene Accession – NP_055047 )
Background:    The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.
Immunogen:    Synthetic peptide of human VAMP2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 1000-5000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cancer, Metabolism, Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human skeletal muscle tissue using 221100(VAMP2 Antibody) at a dilution of 1/50(Cytoplasm).

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-7: NIH/3T3 cell, Mouse heart tissue, Jurkat, A172, Hela, Mouse brain tissue, RAW264.7 cell lysates;
Primary antibody: 221100(VAMP2 Antibody) at dilution 1/1000;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 20 seconds
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