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VDAC3 Rabbit pAb

Anti-VDAC3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S211745

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S211745
Product Name:   Anti-VDAC3 Rabbit Polyclonal Antibody
Synonyms:   VDAC-3; HD-VDAC3
UNIPROT ID:   Q9Y277 (Gene Accession – BC056870 )
Background:    This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene.
Immunogen:    Fusion protein of human VDAC3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 211745(VDAC3 Antibody) at a dilution of 1/55(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 211745(Anti-VDAC3 Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 211745(Anti-VDAC3 Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with fusion protein and then with D123531(Anti-VDAC3 Antibody) at dilution 1/55.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: TM4, LNCAP cell lysates;
Primary antibody: 211745(VDAC3 Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 10 seconds
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