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Vinculin Rabbit mAb

Anti-Vinculin Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263072

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263072
Product Name:   Anti-Vinculin Rabbit Monoclonal Antibody
Synonyms:   VCL; Vinculin; Metavinculin
UNIPROT ID:   P18206
Background:    Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development. Three structural vinculin domains include an amino-terminal head, a short, flexible proline-rich region and a carboxy-terminal tail. In the inactive state, the head and tail domains of vinculin interact to form a closed confirmation. The open and active form of vinculin translocates to focal adhesions where it is thought to be involved in anchoring F-actin to the membrane and regulation of cell migration.
Immunogen:    A synthetic peptide of human Vinculin
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R04-8F9
MW:    Calculated MW: 124 kDa; Observed MW: 124 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Vinculin(green) in Hela using Vinculin antibody,and DAPI(blue)

Western blot analysis of Vinculin in K562, rat Brain, C6, 3T3, Hela lysates using Vinculin antibody.
          Publications