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VPS33A Rabbit pAb

Anti-VPS33A Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218015

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218015
Product Name:   Anti-VPS33A Rabbit Polyclonal Antibody
Synonyms:   MPSPS
UNIPROT ID:   Q96AX1 (Gene Accession – BC016617 )
Background:    This gene encodes a tethering protein and a core subunit of the homotypic fusion and protein sorting (HOPS) complex. The HOPS complex and a second endosomal tethering complex called the class C core vacuole/endosome tethering (CORVET) comple,x perform diverse functions in endocytosis including membrane tethering, RabGTPase interaction, activation and proofreading of synaptic-soluble N-ethylmaleimide-sensitive factor attachment receptor (SNARE) assembly to drive membrane fusion, and endosome-to-cytoskeleton attachment. The HOPS complex controls endosome maturation as well as endosome traffic to the lysosome. This complex is essential for vacuolar fusion and is required for adaptor protein complex 3-dependent transport from the golgi to the vacuole. The encoded protein belongs to the Sec1/Munc18 (SM) family of SNARE-mediated membrane fusion regulators. Naturally occurring mutations in this gene are associated with a novel mucopolysaccharidosis-like disease.
Immunogen:    Fusion protein of human VPS33A
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 100-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer tissue using 218015(VPS33A Antibody) at a dilution of 1/80(Cytoplasm and Cell membrane).
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